Evidence-Based Hormone Therapies

Calcitonin

Calcitonin, the hormone made by the C cells of the thyroid gland helps prevent osteoporosis. It reduces bone resorption by inhibiting the bone-resorbing osteoclasts and increases bone density.

Low quality of life and fatigue: the improvement with calcitonin treatment (2 references)
  1. Esenyel M, İçağasıoğlu A, Esenyel CZ. Effects of calcitonin on knee osteoarthritis and quality of life. Rheumatol Int. 2013 Feb;33(2):423-7.
  2. Shohrati M, Bayat N, Saburi A, Abbasi Z. Effect of nasal calcitonin on the health-related quality of life in postmenopause women affected with low bone density. Iran Red Crescent Med J. 2015 Jul 31;17(7).
Sleep disorders and insomnia: the improvement with calcitonin treatment (case report) (1 reference)
  1. Henriksen K, Byrjalsen I, Andersen JR, Bihlet AR, Russo LA, Alexandersen P, Valter I, Qvist P, Lau E, Riis BJ, Christiansen C, Karsdal MA; SMC021 investigators. A randomized, double-blind, multicenter, placebo-controlled study to evaluate the efficacy and safety of oral salmon calcitonin in the treatment of osteoporosis in postmenopausal women taking calcium and vitamin D. Bone. 2016 Oct;91:122-9.
Migraine: prevention with calcitonin treatment (4 references)
  1. Gennari C, Chierichetti MS, Gonnelli S, Vibelli C, Montagnani M, Piolini M. Migraine prophylaxis with salmon calcitonin: a cross-over double-blind, placebo-controlled study. Headache. 1986 Jan;26(1):13-6
  2. Micieli G, Cavallini A, Martignoni E, Covelli V, Facchinetti F, Nappi G. Effectiveness of salmon calcitonin nasal spray preparation in migraine treatment. Headache. 1988 Apr;28(3):196-200
  3. Patti F, Scapagnini U, Nicoletti F, Prato A, Millia C, Clementi G. Calcitonin and migraine. Headache. 1986 Apr;26(4):172-4
  4. Brady SI, Kaufman K, Hart LL. Calcitonin in migraine. DICP. 1991;25:1185-6
Sleep disorders and insomnia: the improvement with calcitonin treatment (1 reference)
  1. Nakajima T, Kajimura N, Kato M, Watanabe T, Nakabayashi T, Hori T, Takahashi K. Improving depth and maintenance of sleep with intramuscular calcitonin: A case report. Psychiatry Clin Neurosci. 2002 Aug;56(4):481-2.
Platelet aggregation in vitro and in vivo: the improvement with calcitonin (1 reference)
  1. Pogliani EM, Corghi E, Ortolani S, Girardello R, Vigo PL, Polli IE. Effects of porcine calcitonin on human platelet function. Biomed Pharmacother. 1984;38(2):97-101  
Intermittent claudication, leg pain due to arterial disease: the improvement with calcitonin treatment (1 reference)
  1. Franchi F, Chiarini P, Matassi L, Strazzulla G, Scardi A, Righi D, Nuzzaci G. Effects of calcitonin on limb blood vessels in human obstructive arterial disease. Int J Clin Pharmacol Res. 1983;3(2):115-28
Obesity: the improvement with calcitonin treatment (1 reference)
  1. Chelikani PK, Haver AC, Reidelberger RD. Effects of intermittent intraperitoneal infusion of salmon calcitonin on food intake and adiposity in obese rats. Am J Physiol Regul Integr Comp Physiol. 2007 Nov;293(5):R1798-808.
Knee osteoarthritis: the improvement with calcitonin treatment (4 references)
  1. Esenyel M, İçağasıoğlu A, Esenyel CZ. Effects of calcitonin on knee osteoarthritis and quality of life. Rheumatol Int. 2013 Feb;33(2):423-7.
  2. Armagan O, Serin DK, Calisir C, Dokumacioglu A, Ozgen M, Oner S, Alatas O. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10.
  3. Manicourt DH, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP. Oral salmon calcitonin reduces Lequesne’s algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum. 2006 Oct;54(10):3205-11
  4. Manicourt DH, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP. Oral salmon calcitonin reduces Lequesne’s algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum. 2006 Oct;54(10):3205-11  
Osteoarthritis: the improvement with calcitonin treatment (3 references)
  1. Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Lau EM, Arnold M, Christiansen C. The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study. Osteoarthritis Cartilage. 2010 Feb;18(2):150-9
  2. Badurski J. Calcitonin in treating bone and joint lesions–clinical and experimental findings and personal experience. Pol Tyg Lek. 1993 Nov;48 Suppl 3:65-8
  3. Bagger YZ, Tankó LB, Alexandersen P, Karsdal MA, Olson M, Mindeholm L, Azria M, Christiansen C. Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis. Bone. 2005 Sep;37(3):425-30
Adhesive capsulitis (1 reference)
  1. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S
Reflex sympathetic dystrophy syndrome (Continuing pain, allodynia (perception of pain from a nonpainful stimulus), or hyperalgesia (an exaggerated sense of pain) disproportionate to the inciting event, edema, skin blood flow abnormality, or abnormal sweating in the region of the pain since the inciting event), pain, edema, less mobility of joints: the improvement with calcitonin treatment (3 references)
  1. Gobelet C, Meier JL, Schaffner W, Bischof-Delaloye A, Gerster JC, Burckhardt P. Calcitonin and reflex sympathetic dystrophy syndrome. Clin Rheumatol. 1986 Sep;5(3):382-8
  2. Nuti R, Vattimo A, Turchetti V, Martini G, Righi GA. Treatment of Sudeck’s syndrome with human calcitonin. Dtsch Med Wochenschr. 1983 Aug 26;108(34):1281-3
  3. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S
Sudeck’s syndrome (is usually followed by changes in the condition of the skin, which may become shiny. In severe cases, the affected body part may swell): the improvement with calcitonin treatment (4 references)
  1. Ardito S, Musumeci S, Bonfiglio G, Palmucci T. Radioisotopic evaluation of the treatment of Sudek’s syndrome with calcitonin. Ital J Orthop Traumatol. 1978 Apr;4(1):109-14
  2. Mudun A, Bursali A, Oklu T, Araci A, Silahci H, Cantez S. Scintigraphic evaluation of the effectiveness of intranasal calcitonin therapy in Sudeck’s atrophy. Nucl Med Commun. 1993 Sep;14(9):805-9
  3. Münzenberg KJ. Treatment of Sudeck’s syndrome with calcitonin. Dtsch Med Wochenschr. 1978 Jan 6;103(1):26-9
  4. Schürmann M, Vogel T, Gärtner A, Andress HJ, Gradl G.  [Experiences with calcitonin treatment of patients with type I complex regional pain syndrome (CRPS I–Sudeck disease)] Z Orthop Ihre Grenzgeb. 2001 Sep-Oct;139(5):452-7  
Ankylosing spondylitis: the improvement with calcitonin treatment (1 reference)
  1. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S  
Join pain: the relief with calcitonin treatment (1 reference)
  1. Janke A, Badurski J, Stasiewicz J, Sajewicz I, Namiot Z. Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial. Dtsch Z Verdau Stoffwechselkr. 1988;48(5):239-43
Hand pain due to arterial disease or reflex sympathetic dystrophy: the relief with calcitonin treatment (2 references)
  1. Franchi F, Chiarini P, Matassi L, Strazzulla G, Scardi A, Righi D, Nuzzaci G. Effects of calcitonin on limb blood vessels in human obstructive arterial disease. Int J Clin Pharmacol Res. 1983;3(2):115-28.
  2. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S
Paresthesias: the relief with calcitonin treatment (1 reference)
  1. Elsheikh NA, Amr YM. Effect of adding calcitonin to translaminar epidural steroid in degenerative lumbar spinal canal stenosis. Pain Physician. 2016 Mar;19(3):139-46.
Shoulder pain: the relief with calcitonin treatment (1 reference)
  1. Rouhani A, Mardani-Kivi M, Bazavar M, Barzgar M, Tabrizi A, Hashemi-Motlagh K, Saheb-Ekhtiari K. Calcitonin effects on shoulder adhesive capsulitis. Eur J Orthop Surg Traumatol. 2016 Aug;26(6):575-80.
Pain, tenderness, and swelling of the costosternal or sternoclavicular joints (Tietze’s syndrome): the relief with calcitonin treatment (1 reference)
  1. Ricevuti G. Effects of human calcitonin on pain in the treatment of Tietze’s syndrome. Clin Ther. 1985;7(6):669-73
Pain, greater pain sensitivity: the relief with calcitonin treatment (2 references)
  1. Badurski J. Calcitonin in treating bone and joint lesions–clinical and experimental findings and personal experience. Pol Tyg Lek. 1993 Nov;48 Suppl 3:65-8.14.
  2. Chiarini P, Matassi L, Fabrizi G.  Calcitonin and somatic pain: influence of the hormone on the algogenic component of experimental cantharidin-induced cutaneous inflammation. Clin Ter. 1978 Sep 15;86(5):451-63.
Tooth pain: the relief with calcitonin treatment (1 reference)
  1. Alarcón JA, Linde D, Barbieri G, Solano P, Caba O, Rios-Lugo MJ, Sanz M, Martin C. Calcitonin gingival crevicular fluid levels and pain discomfort during early orthodontic tooth movement in young patients. Arch Oral Biol. 2013 Jun;58(6):590-5.
Tooth pulp pain: the relief with calcitonin treatment (1 reference)
  1. Yamamoto M, Tachikawa S, Maeno H. Effects of porcine calcitonin on behavioral and electrophysiological responses elicited by electrical stimulation of the tooth pulp in rabbits. Pharmacology. 1982;24(6):337-45. 
High abdominal pain caused by peptic ulcer: the relief with calcitonin treatment (2 references)
  1. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S
  2. Badurski J.  Calcitonin in treating bone and joint lesions–clinical and experimental findings and personal experience. Pol Tyg Lek. 1993 Nov;48 Suppl 3:65-8
Edema and severe pain in patients with type I complex regional pain syndrome (CRPS I–Sudeck disease, Reflex sympathetic dystrophy): the relief with calcitonin treatment (2 references)
  1. Marini F, Veclani G. New therapeutic prospectives in reflex algodystrophy of the legs. Local intradermal calcitonin. Chir Ital. 1984 Oct;36(5):864-71
  2. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S. 
Complex regional pain syndrome type I in severe hemiplegic patients after stroke: the relief with calcitonin treatment (1 reference)
  1. Matayoshi S, Shimodozono M, Hirata Y, Ueda T, Horio S, Kawahira K. Use of calcitonin to prevent complex regional pain syndrome type I in severe hemiplegic patients after stroke. Disabil Rehabil. 2009;31(21):1773-9
Generalized burning pain in the hand or feet of Sudeck’s syndrome: the relief with calcitonin treatment (1 reference)
  1. Ardito S, Musumeci S, Bonfiglio G, Palmucci T. Radioisotopic evaluation of the treatment of Sudek’s syndrome with calcitonin. Ital J Orthop Traumatol. 1978 Apr;4(1):109-14
Radius fracture pain: the relief with calcitonin treatment (1 reference)
  1. Karponis A, Rizou S, Pallis D, Zafeiris CP, Georgiou DF, Galanos A, Giannoulis F, Lyritis GP. Analgesic effect of nasal salmon calcitonin during the early post-fracture period of the distal radius fracture. J Musculoskelet Neuronal Interact. 2015 Jun;15(2):186-9.
Knee pain: the relief with calcitonin treatment (2 references)
  1. Armagan O, Serin DK, Calisir C, Dokumacioglu A, Ozgen M, Oner S, Alatas O. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10.
  2. Esenyel M, İçağasıoğlu A, Esenyel CZ. Effects of calcitonin on knee osteoarthritis and quality of life. Rheumatol Int. 2013 Feb;33(2):423-7. 
Phantom limb amputation pain: the relief with calcitonin treatment (4 references)
  1. Yousef AA, Aborahma AM. The preventive value of epidural calcitonin in patients with lower limb amputation. pain Med. 2017 Sep 1;18(9):1745-1751.
  2. Yousef AA, Aborahma AM. The preventive value of epidural calcitonin in patients with lower limb amputation. pain Med. 2017 Sep 1;18(9):1745-1751.
  3. Humble SR. Calcitonin for acute neuropathic pain associated with spinal cord injury. Anaesth Intensive Care. 2011 Jul;39(4):682-6.
  4. Viana R, Payne MW. Use of calcitonin in recalcitrant phantom limb pain complicated by heterotopic ossification. Pain Res Manag. 2015 Sep-Oct;20(5):229-33.
Osteoporosis pains: the relief with calcitonin treatment (3 references)
  1. Pontiroli AE, Pajetta E, Scaglia L, Rubinacci A, Resmini G, Arrigoni M, Pozza G. Analgesic effect of intranasal and intramuscular salmon calcitonin in post-menopausal osteoporosis: a double-blind, double-placebo study. Aging (Milano). 1994 Dec;6(6):459-63
  2. Isaia GC, Di Stefano M, Sciolla A, Mussetta M, Vassellatti D. Synthetic salmon calcitonin suppositories for the short-term treatment of involutive osteoporosis. Minerva Med. 1995 Mar;86(3):101-4
  3. Pontiroli AE, Pajetta E, Calderara A, Alberetto M, Pozza G, Manganelli V, Resmini G, Tessari L, Maresca V. Intranasal and intramuscular human calcitonin in female osteoporosis and in Paget’s disease of bones: a pilot study. J Endocrinol Invest. 1991 Jan;14(1):47-51
Degenerative vertebral spinal canal stenosis pain, greater pain sensitivity: the relief with calcitonin treatment (1 reference)
  1. Elsheikh NA, Amr YM. Effect of adding calcitonin to translaminar epidural steroid in degenerative lumbar spinal canal stenosis. Pain Physician. 2016 Mar;19(3):139-46.
Vertebral crush pain: the relief with calcitonin treatment (6 references)
  1. Knopp-Sihota JA, Newburn-Cook CV, Homik J, Cummings GG, Voaklander D. Calcitonin for treating acute and chronic pain of recent and remote osteoporotic vertebral compression fractures: a systematic review and meta-analysis. Osteoporos Int. 2012 Jan;23(1):17-38.
  2. Humble SR. Calcitonin for acute neuropathic pain associated with spinal cord injury. Anaesth Intensive Care. 2011 Jul;39(4):682-6.
  3. Appelboom T. Calcitonin in reflex sympathetic dystrophy syndrome and other painful conditions. Bone. 2002 May;30(5 Suppl):84S-86S
  4. Blau LA, Hoehns JD. Analgesic efficacy of calcitonin for vertebral fracture pain. Ann Pharmacother. 2003 Apr;37(4):564-70
  5. Lyritis GP, Tsakalakos N, Magiasis B, Karachalios T, Yiatzides A, Tsekoura M. Analgesic effect of salmon calcitonin in osteoporotic vertebral fractures: a double-blind placebo-controlled clinical study. Calcif Tissue Int. 1991 Dec;49(6):369-72

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Metastatic bone pain: the relief with calcitonin treatment (4 references)
  1. Sasaki F, Uchino J, Hata Y, Sato Y, Konno T, Okuno T, Ohira S, Taguchi K, Fuzisawa J, Oku T. Clinical study of eel calcitonin for relief of pain from metastatic bone lesions. Gan To Kagaku Ryoho. 1991 Mar;18(3):437-42
  2. Okayasu T, Masuda T, Hashimoto M, Tanabe T. Clinical study of a synthetic calcitonin derivative (elcatonin) in patients with metastatic bone tumors. Gan To Kagaku Ryoho. 1987 Sep;14(9):2703-9
  3. Miseria S, Torresi U, Piga A, Tummarello D, Belleggia C, Caputi CA, Cellerino R. Analgesia with epidural calcitonin in cancer patients. Tumori. 1989 Apr 30;75(2):183-4
  4. Matsumoto T, Nagata N, Horikoshi N, Adachi I, Ohashi Y, Ogata E. Comparative study of incadronate and elcatonin in patients with malignancy-associated hypercalcaemia. J Int Med Res. 2002 May-Jun;30(3):230-43
Paget disease pain: the relief with calcitonin treatment (1 reference)
  1. Pontiroli AE, Pajetta E, Calderara A, Alberetto M, Pozza G, Manganelli V, Resmini G, Tessari L, Maresca V. Intranasal and intramuscular human calcitonin in female osteoporosis and in Paget’s disease of bones: a pilot study. J Endocrinol Invest. 1991 Jan;14(1):47-51
Muscle damage and atrophy due to corticoids: the accelerated healing with calcitonin treatment (1 reference)
  1. Higuchi K, Hayashi K, Shimoozaki Y, Ohtsuka A, Tomita Y. Calcitonin reduced corticosterone-induced muscle proteolysis. J Nutr Sci Vitaminol (Tokyo). 1995 Oct;41(5):545-52
Achilles’ tendon damage: the accelerated healing with calcitonin treatment (1 reference)
  1. Petrou CG, Karachalios TS, Khaldi L, Karantanas AH, Lyritis GP. Calcitonin effect on Achilles tendon healing. An experimental study on rabbits. J Musculoskelet Neuronal Interact. 2009 Jul-Sep;9(3):147-54
Osteoporosis and osteopenia: the association with lower calcitonin levels (5 references)
  1. Zhang M, Li Y, Ma Q, Mao W, Gao Y, Liu Y, Liang B. Relevance of parathyroid hormone (PTH), vitamin 25(OH)D3, calcitonin (CT), bone metabolic markers, and bone mass density (BMD) in 860 female cases. Clin Exp Obstet Gynecol. 2015;42(2):129-32.
  2. Foresta C, Scanelli G, Zanatta GP, Busnardo B, Scandellari C. Reduced calcitonin reserve in young hypogonadic osteoporotic men. Horm Metab Res. 1987 Jun;19(6):275-7
  3. Melton LJ 3rd, Ardila E, Crowson CS, O’Fallon WM, Khosla S. Fractures following thyroidectomy in women: a population-based cohort study. Bone. 2000 Nov;27(5):695-700
  4. Chuchalin AG, Suleimanov SSh, Gasanov SG, Grigor’ev AI, Shmushkovich BI. Study of calcitonin and parathyroid hormone in patients with bronchial asthma with steroid-induced osteoporosis. Probl Endokrinol (Mosk). 1983 Sep-Oct;29(5):19-20
  5. Cappelli C, Cottarelli C, Cumetti D, Agosti B, Gandossi E, Rizzoni D, Agabiti Rosei E. Bone density and mineral metabolism in calcitonin-deficiency patients. Minerva Endocrinol. 2004 Mar;29(1):1-10
Osteoporosis and osteopenia: the improvement with calcitonin treatment (20 references)
  1. Binkley N, Bone H, Gilligan JP, Krause DS. Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial. Osteoporos Int. 2014 Nov;25(11):2649-56.
  2. Rizzoli R, Sigaud A, Azria M, Herrmann FR. Nasal salmon calcitonin blunts bone microstructure alterations in healthy postmenopausal women. Osteoporos Int. 2015 Jan;26(1):383-93.
  3. Karsdal MA, Byrjalsen I, Riis BJ, Christiansen C. Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin. BMC Clin Pharmacol. 2008 Dec 4;8:12
  4. Wang SX, Li H. Salmon calcitonin in prevention of osteoporosis in maintenance dialysis patients. Chin Med J (Engl). 2008 Jul 20;121(14):1280-4
  5. Wang SX, Li H. Effects of salmon calcitonin in treatment of osteoporosis in patients undergoing dialysis. Zhonghua Yi Xue Za Zhi. 2008 Feb 5;88(6):387-90

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Vertebral fractures: the improvement with calcitonin treatment (4 references)
  1. Tanaka S, Yoshida A, Kono S, Ito M. Effectiveness of monotherapy and combined therapy with calcitonin and minodronic acid hydrate, a bisphosphonate, for early treatment in patients with new vertebral fractures: An open-label, randomized, parallel-group study. J Orthop Sci. 2017 May;22(3):536-541.
  2. Ishida Y, Kawai S. Comparative efficacy of hormone replacement therapy, etidronate, calcitonin, alfacalcidol, and vitamin K in postmenopausal women with osteoporosis: The Yamaguchi Osteoporosis Prevention Study. Am J Med. 2004 Oct 15;117(8):549-55
  3. Rico H, Revilla M, Hernandez ER, Villa LF, Alvarez de Buergo M. Total and regional bone mineral content and fracture rate in postmenopausal osteoporosis treated with salmon calcitonin: a prospective study. Calcif Tissue Int. 1995 Mar;56(3):181-5
  4. Villareal DT, Rupich RC, Pacifici R, Griffin MG, Maggio D, Avioli LV, Civitelli R. Effect of estrogen and calcitonin on vertebral bone density and vertebral height in osteoporotic women. Osteoporos Int. 1992 Mar;2(2):70-3
Radius fractures: the improvement with calcitonin treatment (1 reference)
  1. Karponis A, Rizou S, Pallis D, Zafeiris CP, Georgiou DF, Galanos A, Giannoulis F, Lyritis GP. Analgesic effect of nasal salmon calcitonin during the early post-fracture period of the distal radius fracture. J Musculoskelet Neuronal Interact. 2015 Jun;15(2):186-9.
Kidney stones, calcium deposits in the tissues due to hypercalcemia: the improvement with calcitonin treatment (1 reference)
  1. Meythaler JM, Korkor AB, Nanda T, Kumar NA, Fallon M. Immobilization hypercalcemia associated with Landry-Guillain-Barré syndrome. Successful therapy with combined calcitonin and etidronate. Arch Intern Med. 1986 Aug;146(8):1567-71
Hyperparathyroidism: the improvement with calcitonin treatment (2 references)
  1. Stone MD, Marshall DH, Hosking DJ, Garcia-Himmelstine C, White DA, Worth HG. Comparison of low-dose intramuscular and intravenous salcatonin in the treatment of primary hyperparathyroidism. Bone. 1992;13(3):265-71
  2. Torring O, Bucht E, Sjostedt U, Sjoberg HE. Salmon calcitonin treatment by nasal spray in primary hyperparathyroidism. Bone. 1991;12(5):311-6.
Paget’s disease: the improvement with calcitonin treatment (3 references)
  1. Gonzalez D, Vega E, Ghiringhelli G, Mautalen C. Comparison of the acute effect of the intranasal and intramuscular administration of salmon calcitonin in Paget’s disease. Calcif Tissue Int. 1987 Dec;41(6):313-5
  2. Pontiroli AE, Pajetta E, Calderara A, Alberetto M, Pozza G, Manganelli V, Resmini G, Tessari L, Maresca V. Intranasal and intramuscular human calcitonin in female osteoporosis and in Paget’s disease of bones: a pilot study. J Endocrinol Invest. 1991 Jan;14(1):47-51
  3. Chapuy MC, Meunier P, Terrier M, David L, Vignon G. Short-term biological effects of synthetic salmon calcitonin in Paget’s disease. Influence of posology. Pathol Biol (Paris). 1975 May;23(5):349-59
Serum calcitonin (8 references) 
  1. Zhan Z, Meng X, Chen L, Zhou X, Liu S. The setting up of human serum calcitonin radioimmunoassay and its clinical Application. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1997 Jun;19(3):236-40
  2. Emmertsen K, Marqversen J, Jensen FT, Hansen HH. Radioimmunoassay of calcitonin in unextracted human serum: a sensitive method. Scand J Clin Lab Invest. 1982 Nov;42(7):539-44
  3. Suzuki H. Calcitonin levels in normal individuals with new highly sensitive chemiluminescent enzyme immunoassay. J Clin Lab Anal. 1998;12(4):218-22.
  4. Stepan JJ, Zikan V. Calcitonin load test to assess the efficacy of salmon calcitonin. Clin Chim Acta. 2003 Oct;336(1-2):49-55
  5. Ismailov SI, Piulatova NR. Postoperative calcitonin study in medullary thyroid carcinoma. Endocr Relat Cancer. 2004 Jun;11(2):357-63

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